Normalized Interferon Signatures and Clinical Improvements by IFNAR1 Blocking Antibody (Anifrolumab) in Patients with Type I Interferonopathies

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Investigators showed in four patients with STING–associated vasculopathy with onset in infancy and one with chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperatures syndrome that blockade of the IFNAR1 receptor exerted an additive effect over JAK-inhibitor alone.
[Journal of Clinical Immunology]
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