METTL3 Confers Oxaliplatin Resistance Through the Activation of G6PD-Enhanced Pentose Phosphate Pathway in Hepatocellular Carcinoma

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Employing siRNA library screening, scientists identified that silencing the m6A writer methyltransferase-like 3 (METTL3) significantly enhanced the sensitivity to oxaliplatin in both in vivo and in vitro hepatocellular carcinoma models.
[Cell Death & Differentiation]
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