NewslettersProstate Cell NewsIMPA1-Derived Inositol Maintains Stemness in Castration-Resistant Prostate Cancer via IMPDH2 ActivationBy Emily Salmini - October 29, 2024025Scientists showed that IMPA1-derived inositol enriched in prostate cancer stem cells (PCSC) was a key metabolite crucially maintaining PCSCs for CRPC progression and androgen ablation therapy resistance.[Journal of Experimental Medicine]Abstract