MICU2 Up-Regulation Enhances Tumor Aggressiveness and Metabolic Reprogramming during Colorectal Cancer Development

Scientists describe the role of MICU2 in cell proliferation and invasion using in vitro and in vivo models of human CRC. Transcriptomic analysis demonstrated an increase in MICU2 expression and the MICU2/MICU1 ratio in advanced CRC and CRC-derived metastases.