LIF Promotes Sec15b-Mediated STAT3 Exosome Secretion to Maintain Stem Cell Pluripotency in Mouse Embryonic Development

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Investigators reported that in mESC, STAT3 underwent multivesicular endosomes translocation and subsequent secretion and LIF-activated STAT3 was acetylated on K177/180 and phosphorylated on Y293 residues within the N-terminal coiled-coil domain.
[Advanced Science]
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