Renal Remodeling by CXCL10-CXCR3 Axis-Recruited Mesenchymal Stem Cells and Subsequent IL4I1 Secretion in Lupus Nephritis

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Scientists elucidated that the migration of human umbilical cord-MSCs to the lupus nephritis kidney was driven by elevated levels of CXCL10, predominantly produced by glomerular vascular endothelial cells through the IFN-γ/IRF1-KPNA4 pathway.
[Signal Transduction and Targeted Therapy]
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