Rhaponticin Suppresses the Stemness Phenotype of Gastric Cancer Stem-Like Cells CD133+/CD166 + by Inhibiting Programmed Death-Ligand 1

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Gastric cancer stem cells were isolated using CD133 and CD166 markers with magnetic bead separation method. Then they evaluated their response to the IC50 concentrations of rhaponticin, and effects on cell proliferation, migration, invasion, and stemness were measured.
[BMC Gastroenterology]
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