Inhibition of zDHHC7-Driven Protein S-Palmitoylation Prevents Cognitive Deficits in an Experimental Model of Alzheimer’s Disease

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Researchers showed that brain insulin resistance epigenetically caused zDHHC7 overexpression and induced aberrant S-palmitoylation of proteins regulating synaptic function and amyloid-β metabolism.
[Proceedings of The National Academy of Sciences of The United States of America]
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