Vasculogenic Skin Reprogramming Requires TET-Mediated Gene Demethylation in Fibroblasts for Rescuing Impaired Perfusion in Diabetes

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Human dermal fibroblasts responded to Etv2, Foxc2, and Fli1 nanoelectroporation with elevated expression of endothelial genes in vitro, which was linked to increased ten-eleven translocase 1/2/3 (TET) expression.
[Nature Communications]
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