miR-122/NEGR1 Axis Contributes Colorectal Cancer Liver Metastasis by PI3K/AKT Pathway and Macrophage Modulation

Scientists identified new targets for predicting and treating colorectal cancer (CRC) liver metastasis (CRLM). Bioinformatics analysis highlighted the miR-122/NEGR1 axis as crucial in CRLM. In vitro assays explored the impact of this axis on CRC cell proliferation, invasion, and migration.