USP19 Potentiates Autophagic Cell Death via Inhibiting mTOR Pathway through Deubiquitinating NEK9 in Pancreatic Cancer

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Scientists identified that ubiquitin-specific protease 19 (USP19) was downregulated in pancreatic tumor tissues and forced expression of USP19 diminished tumorigenicity of pancreatic cancer.
[Cell Death & Differentiation]
AbstractGraphical Abstract