Single-Cell RNA Sequencing Reveals Key Regulators and Differentiation Trajectory of iPSC-Derived Cardiomyocytes

To elucidate the dynamic gene regulatory networks and pivotal regulators involved in the cardiomyocyte differentiation process, scientists conducted an analysis of single-cell RNA sequencing data obtained from the reprogramming of two human induced pluripotent stem cell lines into cardiomyocytes.