Nicotine Enhances the Stemness and Tumorigenicity in Intestinal Stem Cells via Hippo-YAP/TAZ and Notch Signal Pathway

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Researchers identified a nicotine-triggered pathway regulating the stemness and tumorigenicity of intestinal stem cells and suggested the use of dibenzazepine as a potential therapeutic strategy for treating intestinal tumors.
[eLife]
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