Anti-Herpetic Tau Preserves Neurons via the cGAS-STING-TBK1 Pathway in Alzheimer’s Disease

Researchers detected herpes simplex virus 1 (HSV-1)-associated proteins in human brain samples. Expression of the herpesvirus protein, immediate-early infection cell protein, increased with Alzheimer’s disease severity and strongly colocalized with p-tau but not with Aβ.