Unleashing the Power of Immune Checkpoints: A New Strategy for Enhancing Treg Cells Depletion to Boost Antitumor Immunity

The authors examine the complex relationship between immune checkpoints such as PD-1/PD-L1, CTLA-4, TIGIT, TIM-3, and OX40, and Tregs in the tumor microenvironment, and how they influence tumor immunity.