DOC2b Enrichment Mitigates Proinflammatory Cytokine-Induced CXCL10 Expression by Attenuating IKKβ and STAT-1 Signaling in Human Islets

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Investigators applied biochemical studies, qPCR, proteomics, and immuno-confocal microscopy to determine the underlying protective mechanisms of double C 2 like domain beta (DOC2b) in β-cells.
[Metabolism Clinical and Experimental]
AbstractGraphical Abstract