Tattooed Human In Vitro Skin Model for Testing the Biocompatibility of Tattoo Inks and Healing Progression after Tattooing

Researchers described an in vitro 3D human skin model that was tattooed with black and red ink. Biocompatibility including analysis of cytotoxicity, gene expression patterns of proinflammatory cytokines, and proliferation markers were investigated over a period of seven days.