Artificial Cornea Substitute Based on Hydrogel Skeletons with Natural Stromal Hierarchical Structure and Extracellular Matrix for Sutureless Transplantation

Researchers prepared humanized corneal stroma-like adhesive patches (HCSPs) through a multi-step process. In rabbit models of lamellar keratoplasty and microperforation repair, HCSPs accelerated epithelial healing, minimized suture-associated complications, and maintained structural stability.