Preclinical Evaluation of Zirconium-89 Labeled Anti-Trop2 Antibody-Drug Conjugate (Trodelvy) for Imaging in Gastric Cancer and Triple-Negative Breast Cancer

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Leveraging the enhanced specificity of antibody-drug conjugate, researchers conducted the first immunoPET imaging study of Trop2 expression in gastric cancer and TNBC models using 89Zr-labeled Trodelvy.
[European Journal of Nuclear Medicine and Molecular Imaging]
Abstract