Targeting ABCD1-ACOX1-MET/IGF1R Axis Suppresses Multiple Myeloma

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Scientists revealed a specific metabolic vulnerability of multiple myeloma cells and identified a targetable axis linking very long chain fatty acid metabolism to the regulation of MET proto-oncogene (MET) and insulin-like growth factor 1 receptor (IGF1R) activity.
[Leukemia]
Abstract