Phosphoproteomics Delineates Hepatocellular Carcinoma Subtypes and Pinpoints Therapeutic Targets

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Scientists conducted an in-depth analysis of a clinical cohort of HCC using high-coverage phosphoproteomic. Therapeutic targets were validated using liver cancer cell lines and HCC patient-derived xenograft mouse models that corresponded to the phosphoproteomic subtypes of HCC.
[Hepatology]
AbstractGraphical Abstract