NewslettersCell Therapy NewsA Universal and Wide-Range Cytosine Base Editor via Domain-Inlaid and Fidelity-Optimized CRISPR-FrCas9By Noshin Noorjahan - February 3, 20250111A series of iteratively improved cytosine base editors were constructed using the FrCas9 nickase with the unique protospacer adjacent motif palindromic structure to alleviate these challenges.[Nature Communications]Full Article