Integrative Genomic Analysis of DLBCL Identifies Immune Environments Associated with Bispecific Antibody Response

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An integrative, multi-omic approach was applied to multiple large independent datasets in order to characterize diffuse large B-cell lymphoma (DLBCL) immune environments, and to define their association with tumor cell-intrinsic genomic alterations and outcomes to CD19-directed CAR T-cell and CD20 x CD3 BsAb therapies.
[Blood]
Abstract