NewslettersPancreatic Cell NewsAtf4 Protects Islet β-Cell Identity and Function Under Acute Glucose-Induced Stress but Promotes β-Cell Failure in the Presence of Free Fatty AcidBy Noshin Noorjahan - February 4, 2025014Researchers showed that Atf4 expression in β-cells was minimally required for glucose homeostasis in juvenile and adolescent mice but it is needed for β-cell function during aging and under obesity-related metabolic stress.[Diabetes]Abstract