Exosome Platform with Three-in-One Functionality of mRNA Therapy, Immune Checkpoint Blockade, and Mild Photothermal Therapy for the Treatment of Triple-Negative Breast Cancer

Investigators presented a multifunctional nanotherapeutic platform designed to combine cytokine-sensitized mild photothermal therapy, immune checkpoint blockade (ICB), and interleukin-2 mRNA therapy to reprogram the tumor microenvironment, thereby improving the efficacy of ICB therapy in TNBC.