NewslettersImmune Regulation News Biotin Receptor-Targeting PtIV Oxygen Carrying Prodrug Amphiphile for Alleviating Tumor Hypoxia Induced Immune Chemotherapy SuppressionArticle link copied! By Jamie Kang - March 7, 2025 0 31 Investigators demonstrated that the cytotoxic effects of the biotin receptor-targeting PtIV prodrug and increased oxygen levels synergistically reversed the tumor immune microenvironment, leading to improved antitumor efficacy. [ACS Nano ] AbstractGraphical Abstract