Engineered Human Myogenic Cells in Hydrogels Generate Innervated Vascularized Myofibers within Dystrophic Mouse Muscle on Long-Term Engraftment

Scientists developed a clinically relevant transplantation strategy synergizing hydrogel-mediated delivery and engineered human myogenic progenitor cells generated from CRISPR-corrected Duchenne muscular dystrophy patient-derived pluripotent stem cells.