Loss of Socs2 Improves Molecular Responses to IFNα in a Mouse Model of Myeloproliferative Neoplasms Driven by JAK2-V617F

Researchers investigated the role of Socs2, a negative regulator of cytokine signaling, in modulating the response to pegIFNα in a JAK2-V617F mouse model of myeloproliferative neoplasms.