Direct Inhibition of the TXNIP-NLRP3-GSDMD Pathway Reduces Pyroptosis in Colonocytes and Alleviates Ulcerative Colitis in Mice by the Small Compound PEITC

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Researchers evaluated the therapeutic potential of phenethyl isothiocyanate in the treatment of ulcerative colitis and the underlying mechanisms.
[Acta Pharmacologica Sinica]
Abstract