Mesenchymal Stem Cells and Fibroblasts Contribute to Microvascular Proliferation in Glioblastoma and Are Correlated with Immunosuppression and Poor Outcome

Researchers performed single cell RNA-sequencing on paired CD45–CD105+ vascular/perivascular stromal cells and CD45+CD105± immune cells from 16 primary glioma patient samples, both with and without microvascular proliferation.