CXCL Gene Clusters Regulated by Enhancer-Mediated DNA Looping Alteration in Pancreatic Cancer Cells

Scientists determined that the expression of C-X-C motif chemokine ligand 8 (CXCL8), CXCL6, CXCL4L1, CXCL1, CXCL4, CXCL7, CXCL5, CXCL3, and CXCL2 was up-regulated, whereas CXCL9, CXCL10, and CXCL11 were down-regulated in pancreatic cancer cells compared with normal duct epithelial cells.