An Erythroid-Biased FOS^hi Hematopoietic Multipotent Progenitor Subpopulation Contributes to Adaptation to Chronic Hypoxia

Scientists performed single-cell RNA sequencing to analyze hematopoietic stem and progenitor cells and erythroid cells in a mouse model of high-altitude polycythemia mimicking long-term high-altitude hypoxia exposure.