Rewiring of SINE-MIR Enhancer Topology and Esrrb Modulation in Expanded and Naive Pluripotency

Researchers explored the utilization of transposable elements (TE)-derived enhancers in naïve and expanded pluripotent states by integrative analysis of genome-wide Hi-C-defined enhancer interactions, H3K27ac HiChIP profiling, and CRISPR-guided TE proteomics landscape.