METTL3-Dependent m6A RNA Methylation Regulates Transposable Elements and Represses Human NaïVe Pluripotency through Transposable Element-Derived Enhancers

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Using a METTL3 inducible knockout system, researchers uncovered that, unlike in mESCs, METTL3 was indispensable for hPSC maintenance.
[Nucleic Acids Research]
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