Suppression of the Prostaglandin I2–Type 1 Interferon Axis Induces Extramedullary Hematopoiesis to Promote Cardiac Repair after Myocardial Infarction

To assess the role of spleen extramedullary hematopoiesis (EMH) in myocardial infarction (MI), scientists constructed a Tcf21^CreER Scf^flox/flox MI mouse model with inhibited EMH.