OTUD1 Positively Regulates Microglia Neuroinflammation and Promotes the Pathogenesis of Alzheimer’S Disease by Deubiquitinating C/EBPβ

Investigators found that the levels of deubiquitinating enzyme ovarian tumor deubiquitinase 1 (OTUD1), are upregulated in Alzheimer’s disease model mice and amyloid-beta-induced microglia.