LEC2 Induces Somatic Cell Reprogramming through Epigenetic Activation of Plant Cell Totipotency Regulators

Scientists showed that during somatic embryogenesis induced by overexpressing the totipotency-regulating transcription factor LEAFY COTYLEDON2 (LEC2) in Arabidopsis, CHH hypermethylation is deposited by the LEC2-activated RNA-directed DNA methylation pathway.