Dusp14-Mediated Dephosphorylation of MLKL Protects against Cardiomyocyte Necroptosis in Hypothyroidism-Induced Heart Failure

Dual specificity phosphatase 14 (Dusp14) knockout mice were generated, and adeno-associated virus–mediated cardiomyocyte-specific overexpression of Dusp14 was used in combination with related cellular experiments to investigate the protective effects of Dusp14 on hypothyroidism-induced heart failure.