N-Glycosylated LTβR Increases the Th17/Treg Cell Ratio in Liver Cancer by Blocking RORC Ubiquitination and FOXP3 Transcription

Investigators employed primary or subcutaneous mouse hepatocellular carcinoma (HCC) models and flow cytometry to study the impact of conditional knock-in of Ltbr on CD4⁺ T cell differentiation and response, particularly the Th17/Treg cell ratio, and its influence on HCC progression.