FOXP1 Contributes to Murine Hematopoietic Stem Cell Functionality

Investigators showed that loss of hematopoietic-specific factor forkhead box P1 (FOXP1) expression leads to attrition of the HSC and multipotent progenitor (MPP)-1 compartment in parallel with enhancement of myeloid-biased MPP3 in adult bone marrow and fetal liver.