Sohlh1 Modulates the Stemness and Differentiation of Glioma Stem-Like Cells by Inactivation of Wnt/β-Catenin Signaling Pathway via SFRP1

Scientists demonstrated that Sohlh1 functioned through the SFRP1/Wnt/β-catenin signalling pathway and led to the consequent suppression of glioma stem-like cells (GSLC) stemness and the promotion of GSLC differentiation in vitro and in vivo.