Combined Analysis of Somatic Mutations and Gene Expression Reveals Nuclear Speckles-Associated Enhanced Stemness in Gingivobuccal Carcinoma under DNA Damage Response

An RNA-sequencing data-based combined analysis of somatic mutations and gene expression was performed to explore the role of CSCs in disease progression using the novel Indian-origin Gingivobuccal oral squamous cell carcinoma cell line ‘IIOC019’ from a patient with tobacco-chewing habit.