Sodium/Hydrogen Exchanger 8 Affects Sheet Migration of Human Intestinal Epithelial Cells (HT29-MTX) by Influencing the Actin Cytoskeletal Rearrangement

Since ulcerative colitis is characterized by repeated mucosal injury, scientists investigated the role of gastrointestinal Na⁺/H⁺ transporter 8 (NHE8) in intestinal wound repair, by accessing its effect on intracellular pH regulation, cell proliferation and migration.