SREBP1 Deficiency Aggravates Vascular Calcification via iASPP-Triggered Ferroptosis of Vascular Smooth Muscle Cells

Bioinformatics analysis was employed to mine the dataset and screen sterol regulatory element-binding protein 1 (SREBP1) related to ferroptosis and vascular calcification. Quantitative real-time polymerase chain reaction, western blotting, immunofluorescence, and immunohistochemistry were used to analyze gene expression.