A Novel Oncogene, Leucine-Rich Repeat Protein 1, Mediates Hypoxia-Induced Hepatocellular Carcinoma Progression

With findings in bioinformatic analysis, reseachers further validated the involvement of leucine rich repeats protein 1 (LRR1) in HCC progression by cellular experiments. The expression of LRR1 is significantly upregulated in HCC compared to normal liver tissues and cell line.