Palmitoylethanolamide (PEA) Induces an Increase in Spleen Regulatory T Cells, Reduces CD8+ Cells and TNF-α Levels in Target Organs, and Protects Mice from Graft-Versus-Host Disease-Related Mortality through PPAR Activation without Compromising the Graft-Versus-Tumor Response

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Researchers found that palmitoylethanolamide created an immunoregulatory environment in the spleen by reducing the activation of CD3+CD4+ cells.
[Immunology]
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