Modeling Mesenchymal Stromal Cell Support to Hematopoiesis within a Novel 3D Artificial Marrow Organoid System

The authors reported an original, fully-human in vitro 3D model of the bone marrow microenvironment dedicated to study interactions taking place between mesenchymal stromal cells and hematopoietic stem and progenitor cells during the hematopoietic differentiation.