Direct Lineage Reprogramming of Fibroblasts into Functional Keratinocyte-Like Cells via BMI1 and FGFR2b for Diabetic Wound Repair

Researchers established a novel reprogramming approach using a combination of two factors, BMI1 and FGFR2b, to induce fibroblast-to-keratinocyte-like cells conversion in vitro and delivered via adeno-associated virus 9 in vivo.