Autophagy-Targeted NBR1-P62/SQSTM1 Complexes Promote Breast Cancer Metastasis by Sequestering ITCH

By
Jamie Kang
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0
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Investigators showed that autophagy normally suppresses breast cancer metastasis by enabling the clearance of NBR1–p62/SQSTM1 complexes that instruct p63-mediated pro-metastatic basal differentiation programs.
[Nature Cell Biology]
Abstract