Astrocytic RIPK3 Exerts Protective Anti-Inflammatory Activity in Mice with Viral Encephalitis by Transcriptional Induction of Serpins

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Investigators used mouse genetic tools to induce astrocyte-specific deletion, overexpression, and chemogenetic activation of RIPK3 to demonstrate an anti-inflammatory function for astrocytic RIPK3.
[Science Signaling]
Abstract